"I started with 50mg sildenafil. Practitioner moved me to daily tadalafil after a month because the spontaneity matters. Best change I've made in five years."
- BRIAN, 44, ON TADALAFIL 5MG DAILY
COMPARISON · ED
Bionomy ED, vs the rest.
A clear comparison of generic sildenafil and tadalafil pricing, daily vs as-needed options, and the membership fees you only find on the cancellation page.
Take the 4-minute intakeSIDE BY SIDE
The numbers nobody puts in one table.
Bionomy
Clinic / urology
Other DTC brands
Sildenafil 50mg
$59/mo
$20–$80/pill OTC
$60–$99/mo
Tadalafil 5mg daily
$89/mo
$45+ per branded pill
$99–$149/mo
Tri-Mix injection
$149/mo
$200+ from compounders
Rarely offered
PT-141 peptide
$199/mo
Specialty clinic only
Rarely offered
Visit fee
Free intake
$80–$300 urology visit
$0–$59
Membership fee
None
N/A
$15–$40/mo
Practitioner review
24 hours
Appointment-based
24–72 hours
Pay-per-Rx model
Yes
No
No
Pricing reflects representative compounded ED programs in May 2026.
WHAT YOU GET
Six options, one practitioner.
73%
Daily tadalafil works.
In the published clinical data, 73% of men on daily tadalafil report successful intercourse. Most prefer it over the as-needed pattern.
Same
Same molecule as Viagra / Cialis.
Compounded sildenafil is sildenafil. Compounded tadalafil is tadalafil. Same active. Same effect. Different supply chain.
5d
Plain shipping, fast.
Unmarked packaging. 5 business days. Refills automatic. Dose adjustments in chat with the practitioner.
WHAT MEN SAY
Members, in their own words.
"My urologist quoted $250 just to be seen. Bionomy reviewed my intake in 18 hours and shipped sildenafil to me for $59. I felt heard, not processed."
- C., 51, ON SILDENAFIL 50MG
"PDE5 pills weren't enough for me. Tri-Mix changed that. The fact that Bionomy even offers it without an in-person appointment is the whole reason I'm here."
- K., 58, ON TRI-MIX
Compounded medications are not FDA approved. They are prepared by state-licensed pharmacies for individual patients based on a prescription from a licensed practitioner.